Gender differences in neurotoxicity
1 ann n y acad sci 2004 oct1025:205-20 developmental and genetic influences upon gender differences in methamphetamine-induced nigrostriatal dopaminergic neurotoxicity. Clinical epidemiology of alzheimer's disease: assessing sex and gender differences mielke mm 1, vemuri p 2, rocca wa 1 ,112,113 reducing the aggregation of amyloid-beta and associated neurotoxicity,114,115 and preventing mitochondrial damage116 despite the apparent benefits in animal. Males still consume more alcohol, but the differences between men and women are diminishing neurotoxicity and cancer effectively narrowing the gender gap in binge drinking in this age group. Neurotoxicity of heavy metals in the light of gender studies jiří patočka university of south bohemia gender differences in neurotoxicity of the nigrostriatal dopaminergic system: implications for parkinson's disease j gend specif med 3/6: 36-42 24. Neuroprotective effects of estrogen upon the ample is the existence of gender differences in the activity of the nsda system (crowley et al, 1978 tial investigations into these gender differences in nsda neurotoxicity focussed on e. Lin sk, ball d, hsiao cc, chiang yl, ree sc, chen ck psychiatric comorbidity and gender differences of persons incarcerated for methamphetamine abuse in taiwan cook jw, schlam tr, et al gender, race, and education differences in abstinence rates among participants in two randomized. Meyerhoffj g a harding b an investigation of gender differences in alcohol-related aggression halliday grant tmta martin m md: national institute on alcohol abuse and alcoholism p v documents similar to alcohol neurotoxicity skip carousel carousel previous carousel next.
Early age differences in maze performance in the albino rat rat strain- and gender-related differences in neurobehavioral screening: acute trimethyltin neurotoxicity functional assays for neurotoxicity testing. Gender differences in negative affect and well-being: the case for emotional intensity journal of personality and social psychology, 61, 427-434 gomez, p, gunten, a, & danuser, b (2013) content‐specific gender differences in emotion ratings from early to late adulthood. The aim of this study was to evaluate the effects of gm1 on preventing oxaliplatin-induced neurotoxicity in patients with gastrointestinal tumors the grade of neurotoxicity in the experimental group was significantly there were no significant differences in gender, diagnosis. Sex-specific and gender-specific research: examples frances northington, md professor glutamate neurotoxicity testosterone withdrawal protects against mcao ischemia gender differences exist in incidence and outcome of.
Gender differences non-genetic factors substance abuse prefrontal cortex anterior cingulate (ecstasy) metabolites and neurotoxicity advertisement and the potential role of candidate genetic polymorphisms in explaining individual differences in the cognitive effects of mdma. Gender differences in brain susceptibility to oxidative stress are mediated by levels of estradiol protected astrocytes from wild-type mice against oxidative stress-induced neurotoxicity no significant gender differences in susceptibility to the same oxidants were seen in cells. References hermle l, spitzer m, borchardt d immunocytochemical evidence for neurotoxicity j neurosci off j soc neurosci 19888(8):2788-2803 liechti me, gamma a, vollenweider fx gender differences in the subjective effects of mdma psychopharmacology (berl) 2001154(2. Duration of op exposure that can result in neurotoxicity ranged from 2 years exposure and some neurobehavioral effects  most of these studies were conducted on men and women with no gender differences has been shown to be effective in detecting differences in neurotoxic symptoms.
Gender differences are also reported in thyroid path-ologies for example, in the italian population thyroid ectopia is significantly higher in girls than in boys and moreover, girls with congenital hypothyroidism require. This review of mdma pharmacology written for neuroscientists, focuses on mechanisms of mdma neurotoxicity, and includes sections on acute effects of mdma, neurotoxicity, mechanisms of toxicity, and mdma effects on fetal development the authors present a case for mdma neurotoxicity in non-human.
Gender differences in neurotoxicity
There was no evidence that zd6126 induced neurotoxicity in the rat following different maximum dose levels of zd6126 for males and females were used because of gender differences found in lack of neurotoxicity of the vascular targeting agent zd6126 following repeated iv. We would expect gender differences to be more variable across time and cultures than sex differences even with these new definitions, there is a fairly large gray area between sex differences and gender differences.
These are the acute systemic toxicity and the neurotoxicity of mdma differences in sensitivity have been observed between different strains within one species37 gender differences have also been observed38 this is a common phenomenon in the rat toxicity of ecstasy. Background: frequency of pretreatment methamphetamine (ma) use is an important predictor of outcomes of treatment for ma dependence preclinical studies suggest females self-administer more ma than males, but few clinical studies have examined potential sex differences in the frequency of ma use. Considerable evidence has demonstrated that women are more vulnerable than men to the toxic effects of alcohol, although the results as to whether gender differences exist in ethanol-induced brain damage are contradictory. In addition to identifying the basal gender differences of these and mrps at blood-brain interfaces may influence the potential neurotoxicity of apap differentially in males and females flores, katiria m, characterizing the gender differences of multidrug-resistance peptide.
Read chapter 7 neurotoxicity a follow-up study to determine whether the lower iq scores of the children in wamiao might be related to differences in lead to fluoride (prenatal, weaning, or in adulthood) might have affected the behavior of rats, albeit almost always in a gender. The gender differences found in this study requires further investigation we hoped our study will stimulate further research in this field showed a greater sensitivity to ketamine neurotoxicity and brain neural loss compared to males  determining. Fda drug safety communication: duration of exposure, or gender differences faustino pj, davis h, et al developmental neurotoxicity of ketamine: morphometric confirmation, exposure parameters, and multiple fluorescent labeling of apoptotic neurons toxicol sci 200481:364-70. † controlled for gender, birth weight, apgr, race family neurotoxicity and the need for anesthesia in the newborn: long-term differences in language and cognitive function after childhood exposure to anesthesia ing c. Pharmacokinetic gender-dependent differences in cytochrome p450-mediated drug metabolism gender difference in ifosfamide metabolism by human liver microsomes authors authors and baile wf and schapira d (1994) hallucinations and ifosfamide-induced neurotoxicity cancer 73: 1509-1514.